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PEPperPRINT gmbh
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Image Search Results
Journal: The New England journal of medicine
Article Title: Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer
doi: 10.1056/NEJMoa1513749
Figure Lengend Snippet: Patients are screened for I-SPY 2 eligibility. Eligible patients are adaptively randomized to 12 weekly paclitaxel (and trastuzumab if HER2+) cycles (control) or in combination with one of several experimental agents followed by doxorubicin/cyclophosphamide (AC) × 4, with serial biomarkers (biopsies, blood draw and MRI scans) assessed over the course of their therapy. Only patients with HER2− disease were randomized to the veliparib/carboplatin arm.
Article Snippet: Biomarker assessments include the Agendia 70-gene MammaPrint and
Techniques:
Journal: The New England journal of medicine
Article Title: Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer
doi: 10.1056/NEJMoa1513749
Figure Lengend Snippet: Only patients with HER2-negative disease were eligible for randomization to the VC arm. Patients were categorized as received allocated invention if they received at least one dose of experimental (or control) therapy.
Article Snippet: Biomarker assessments include the Agendia 70-gene MammaPrint and
Techniques:
Journal: The New England journal of medicine
Article Title: Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer
doi: 10.1056/NEJMoa1513749
Figure Lengend Snippet: Estimated pCR Rate for the signatures evaluated for V/C vs. concurrent HER2-negative control.
Article Snippet: Biomarker assessments include the Agendia 70-gene MammaPrint and
Techniques: Negative Control
Journal: The New England journal of medicine
Article Title: Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer
doi: 10.1056/NEJMoa1513749
Figure Lengend Snippet: Final predictive probabilities
Article Snippet: Biomarker assessments include the Agendia 70-gene MammaPrint and
Techniques:
Journal: The New England journal of medicine
Article Title: Adaptive Randomization of Veliparib–Carboplatin Treatment in Breast Cancer
doi: 10.1056/NEJMoa1513749
Figure Lengend Snippet: Selected Toxicities
Article Snippet: Biomarker assessments include the Agendia 70-gene MammaPrint and
Techniques: